PZ43 manual clamp-on knife gate valve is suitable for pipes with suspended particles, fiber materials of pulp, sewage, coal slurry, ash cement mixture and other media, relying on the cutting edge gate plate that can cut fiber materials to cut these media. The valve body does not actually have a chamber, the gate plate is raised and lowered in the side guide groove, and pressed against the valve seat by the lugs at the bottom, if high media tightness is required, the O-seal valve seat can be selected to achieve two-way sealing. According to the driving mode, it is divided into manual knife gate valve, pneumatic knife gate valve and electric knife gate valve.